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Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat
Rat lines congenic for the rat N-acetyltransferase 2 [(RAT)Nat2] gene were constructed and characterized. F344 (homozygous Nat2 rapid) males were mated to WKY (homozygous Nat2 slow) females to produce heterozygous F1. F1 females were then backcrossed to F344 males. Heterozygous acetylator female pro...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596689/ https://ncbi.nlm.nih.gov/pubmed/18799801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.023960 |
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