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Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat

Rat lines congenic for the rat N-acetyltransferase 2 [(RAT)Nat2] gene were constructed and characterized. F344 (homozygous Nat2 rapid) males were mated to WKY (homozygous Nat2 slow) females to produce heterozygous F1. F1 females were then backcrossed to F344 males. Heterozygous acetylator female pro...

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Autores principales: Hein, David W., Bendaly, Jean, Neale, Jason R., Doll, Mark A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596689/
https://ncbi.nlm.nih.gov/pubmed/18799801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.023960
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