Antineoplastic Agents 560. Isolation and Structure of Kitastatin 1 from an Alaskan Kitasatospora sp.1

By utilizing a bioassay-guided separation (P388 lymphocytic leukemia and a panel of human cancer cell lines) of fermentation broths from a Kitasatospora sp. collected from a tundra soil sample taken at the shore of the Beaufort Sea, we have isolated three powerful (GI(50) to 0.0006 μg/mL) cancer cel...

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Autors principals: Pettit, George R., Tan, Rui, Pettit, Robin K., Smith, Thomas H., Feng, Song, Doubek, Dennis L., Richert, Linda, Hamblin, John, Weber, Christine, Chapuis, Jean-Charles
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596607/
https://ncbi.nlm.nih.gov/pubmed/17608530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np068072c
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