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Probing Heme Coordination States of Inducible Nitric Oxide Synthase with a Re(I)(imidazole-alkyl-nitroarginine) Sensitizer-Wire

Mammalian inducible nitric oxide synthase (iNOS) catalyzes the production of l-citrulline and nitric oxide (NO) from l-arginine and O(2). The Soret peak in the spectrum of the iNOS heme domain (iNOS(oxy)) shifts from 423 to 390 nm upon addition of a sensitizer-wire, [Re(I)-imidazole-(CH(2))(8)-nitro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Le Nguyen, Yen Hoang, Winkler, Jay R., Gray, Harry B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596599/
https://ncbi.nlm.nih.gov/pubmed/17536854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp071405+
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