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S-Nitrosylated Human Serum Albumin-mediated Cytoprotective Activity Is Enhanced by Fatty Acid Binding

Binding of oleate to S-nitrosylated human serum albumin (SNO-HSA) enhances its cytoprotective effect on liver cells in a rat ischemia/reperfusion model. It enhances the antiapoptotic effect of SNO-HSA on HepG2 cells exposed to anti-Fas antibody. To identify some of the reasons for the increased cyto...

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Autors principals: Ishima, Yu, Akaike, Takaaki, Kragh-Hansen, Ulrich, Hiroyama, Shuichi, Sawa, Tomohiro, Suenaga, Ayaka, Maruyama, Toru, Kai, Toshiya, Otagiri, Masaki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596408/
https://ncbi.nlm.nih.gov/pubmed/18940810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807009200
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