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The Heat Shock Protein Antagonist 17-AAG Potentiates the Activity of Enzastaurin Against Malignant Human Glioma Cells
Recent studies have suggested that the proliferation of malignant gliomas may result from activation of protein kinase C (PKC)-mediated pathways. Enzastaurin (LY317615), an acyclic bisindolylmaleimide, is an oral inhibitor of PKCβ as well as other isoforms. The initial objective of this study was to...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596131/ https://ncbi.nlm.nih.gov/pubmed/18462865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.03.039 |
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