Kinin B(2 )receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice

BACKGROUND: Kinins are important mediators of inflammation and act through stimulation of two receptor subtypes, B(1 )and B(2). Leukocyte infiltration contributes to the pathogenesis of autoimmune inflammation in the central nervous system (CNS), occurring not only in multiple sclerosis (MS) but als...

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Hauptverfasser: Dos Santos, Adriana C, Roffê, Ester, Arantes, Rosa ME, Juliano, Luiz, Pesquero, Jorge L, Pesquero, João B, Bader, Michael, Teixeira, Mauro M, Carvalho-Tavares, Juliana
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596102/
https://ncbi.nlm.nih.gov/pubmed/18986535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-49
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