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Kinin B(2 )receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice
BACKGROUND: Kinins are important mediators of inflammation and act through stimulation of two receptor subtypes, B(1 )and B(2). Leukocyte infiltration contributes to the pathogenesis of autoimmune inflammation in the central nervous system (CNS), occurring not only in multiple sclerosis (MS) but als...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596102/ https://ncbi.nlm.nih.gov/pubmed/18986535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-49 |
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