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Use of recombinant antigens expressed in Escherichia coli K-12 to map B-cell and T-cell epitopes on the immunodominant 65-kilodalton protein of Mycobacterium bovis BCG.

In gene libraries of Mycobacterium bovis BCG, Mycobacterium tuberculosis, and Mycobacterium leprae, recombinants were frequently encountered that expressed an immunodominant 65-kilodalton (kDa) protein antigen that was shown to react with a high proportion of mycobacterium-reactive human and murine...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Thole, J E, van Schooten, W C, Keulen, W J, Hermans, P W, Janson, A A, de Vries, R R, Kolk, A H, van Embden, J D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259448/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2453469/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.6.1633-1640.1988
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