Llwytho...

Efficient Synthesis of Suitably Protected β-Difluoroalanine and γ-Difluorothreonine from L-Ascorbic Acid

Fluorinated amino acids are useful building blocks for the preparation of biologically active peptides and peptidomimetics with increased metabolic stability. We report here the synthesis of two fluorinated amino acids, β-difluoroalanine and γ-difluorothreonine as analogs of Ser and Thr, respectivel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Gongyong, van der Donk, Wilfred A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593874/
https://ncbi.nlm.nih.gov/pubmed/17192080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062401a
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