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One-pot efficient synthesis of N(α)-urethane-protected β- and γ-amino acids

1-[(4-Methylphenyl)oxy]pyrrolidine-2,5-dione and 1-[(4-methylphenyl)oxy]piperidine-2,6-dione react in a Lossen-type reaction with primary alcohols in the presence of triethylamine to furnish corresponding N (α)-urethane-protected β-alanine and γ-aminopropionic acid (GABA), respectively, with excelle...

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Autors principals: Cal, Marta, Jaremko, Mariusz, Jaremko, Łukasz, Stefanowicz, Piotr
Format: Artigo
Idioma:Inglês
Publicat: Springer Vienna 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569585/
https://ncbi.nlm.nih.gov/pubmed/23250684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-012-1443-3
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