Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates

PURPOSE: To compare the ability of alkyl-aryl isothiocyanates (ITCs) to increase the activities of the Phase 2 detoxification enzymes NAD[P]H:quinone acceptor oxidoreductase (NQO1) and glutathione S-transferases (GST) in rat tissues in vivo and in cells in vitro. MATERIALS AND METHODS: 12 alkyl-aryl...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Munday, Rex, Zhang, Yuesheng, Munday, Christine M., Bapardekar, Meghana V., Paonessa, Joseph D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593848/
https://ncbi.nlm.nih.gov/pubmed/18563540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9595-2
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky