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Determination of thymic function directly from peripheral blood: A validated modification to an established method()

The thymus contributes naïve, self MHC reactive, self tolerant T cells to the peripheral immune system throughout life, albeit with a log-linear decline with age. Quantification of thymic function is clinically relevant in the setting of lymphoablation, but a phenotypic marker distinguishing recent...

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Main Authors: Lorenzi, A.R., Patterson, A.M., Pratt, A., Jefferson, M., Chapman, C.E., Ponchel, F., Isaacs, J.D.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593795/
https://ncbi.nlm.nih.gov/pubmed/18854192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2008.09.013
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