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Rab4 facilitates cAMP-stimulated bile acid uptake and NTCP translocation

Cyclic AMP stimulates hepatic bile acid uptake by translocating sodium-taurocholate (TC) cotransporting polypeptide (Ntcp) from an endosomal compartment to the plasma membrane. Rab4 is associated with early endosomes and involved in vesicular trafficking. This study was designed to determine the rol...

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Autors principals: Schonhoff, Christopher M., Thankey, Krishna, Webster, Cynthia R.L., Wakabayashi, Yoshiyuki, Wolkoff, Allan W., Anwer, M. Sawkat
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593787/
https://ncbi.nlm.nih.gov/pubmed/18688880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22495
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