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Alternative Isoform Regulation in Human Tissue Transcriptomes

Through alternative processing of pre-mRNAs, individual mammalian genes often produce multiple mRNA and protein isoforms that may have related, distinct or even opposing functions. Here we report an in-depth analysis of 15 diverse human tissue and cell line transcriptomes based on deep sequencing of...

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Detalhes bibliográficos
Main Authors: Wang, Eric T., Sandberg, Rickard, Luo, Shujun, Khrebtukova, Irina, Zhang, Lu, Mayr, Christine, Kingsmore, Stephen F., Schroth, Gary P., Burge, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593745/
https://ncbi.nlm.nih.gov/pubmed/18978772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07509
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