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Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

The ESCRT machinery, including ESCRT-III, localizes to the midbody and participates in the membrane abscission step of cytokinesis. The ESCRT-III protein CHMP1B is required for recruitment of the MIT domain-containing protein spastin, a microtubule severing enzyme, to the midbody. The 2.5 Å structur...

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Bibliografiska uppgifter
Huvudupphovsmän: Yang, Dong, Rismanchi, Neggy, Renvoisé, Benoît, Lippincott-Schwartz, Jennifer, Blackstone, Craig, Hurley, James H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593743/
https://ncbi.nlm.nih.gov/pubmed/18997780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1512
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