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Closing the circadian negative feedback loop: FRQ-dependent clearance of WC-1 from the nucleus

In Neurospora crassa, a transcription factor, WCC, activates the transcription of frq. FRQ forms homodimers as well as complexes with an RNA helicase, FRH, and the WCC, and translocates into the nucleus to inactivate the WCC, closing the time-delayed negative feedback loop. The detailed mechanism fo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hong, Christian I., Ruoff, Peter, Loros, Jennifer J., Dunlap, Jay C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593610/
https://ncbi.nlm.nih.gov/pubmed/18997062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1706908
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