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Active Alu retrotransposons in the human genome

Alu retrotransposons evolved from 7SL RNA ∼65 million years ago and underwent several rounds of massive expansion in primate genomes. Consequently, the human genome currently harbors 1.1 million Alu copies. Some of these copies remain actively mobile and continue to produce both genetic variation an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bennett, E. Andrew, Keller, Heiko, Mills, Ryan E., Schmidt, Steffen, Moran, John V., Weichenrieder, Oliver, Devine, Scott E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593586/
https://ncbi.nlm.nih.gov/pubmed/18836035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.081737.108
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