Analysis of copy number variants and segmental duplications in the human genome: Evidence for a change in the process of formation in recent evolutionary history

Segmental duplications (SDs) are operationally defined as >1 kb stretches of duplicated DNA with high sequence identity. They arise from copy number variants (CNVs) fixed in the population. To investigate the formation of SDs and CNVs, we examine their large-scale patterns of co-occurrence with d...

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Bibliographic Details
Main Authors: Kim, Philip M., Lam, Hugo Y.K., Urban, Alexander E., Korbel, Jan O., Affourtit, Jason, Grubert, Fabian, Chen, Xueying, Weissman, Sherman, Snyder, Michael, Gerstein, Mark B.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
Subjects:
Letter
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593581/
https://ncbi.nlm.nih.gov/pubmed/18842824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.081422.108
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