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Leptin-induced endothelial dysfunction in obesity

Hyperleptinemia accompanying obesity affects endothelial nitric oxide (NO) and is a serious factor for vascular disorders. NO, superoxide (O(2)(−)), and peroxynitrite (ONOO(−)) nanosensors were placed near the surface (5 ± 2 μm) of a single human umbilical vein endothelial cell (HUVEC) exposed to le...

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Detalhes bibliográficos
Main Authors: Korda, Mykhaylo, Kubant, Ruslan, Patton, Stephen, Malinski, Tadeusz
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593507/
https://ncbi.nlm.nih.gov/pubmed/18689498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00479.2008
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