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An automated segmentation methodology for quantifying immunoreactive puncta number and fluorescence intensity in tissue sections

A number of human brain diseases have been associated with disturbances in the structure and function of cortical synapses. Answering fundamental questions about the synaptic machinery in these disease states requires the ability to image and quantify small synaptic structures in tissue sections and...

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Sonraí Bibleagrafaíochta
Main Authors: Fish, Kenneth N., Sweet, Robert A., Deo, Anthony J., Lewis, David A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593455/
https://ncbi.nlm.nih.gov/pubmed/18793619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.08.060
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