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An automated segmentation methodology for quantifying immunoreactive puncta number and fluorescence intensity in tissue sections
A number of human brain diseases have been associated with disturbances in the structure and function of cortical synapses. Answering fundamental questions about the synaptic machinery in these disease states requires the ability to image and quantify small synaptic structures in tissue sections and...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593455/ https://ncbi.nlm.nih.gov/pubmed/18793619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.08.060 |
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