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An automated segmentation methodology for quantifying immunoreactive puncta number and fluorescence intensity in tissue sections

A number of human brain diseases have been associated with disturbances in the structure and function of cortical synapses. Answering fundamental questions about the synaptic machinery in these disease states requires the ability to image and quantify small synaptic structures in tissue sections and...

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Detalhes bibliográficos
Main Authors: Fish, Kenneth N., Sweet, Robert A., Deo, Anthony J., Lewis, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593455/
https://ncbi.nlm.nih.gov/pubmed/18793619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.08.060
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