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Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Endothelin-1 Expression by a Novel, Redox-Sensitive Mechanism Involving mRNA Stability

The regulation of the synthesis of the endothelial-derived vasoconstrictor endothelin-1 (ET-1) is a complex process encompassing transcriptional as well as mRNA stability mechanisms. We have described recently the existence of a mechanism for the control of ET-1 expression based on the mRNA-destabil...

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Detalhes bibliográficos
Main Authors: Rodríguez-Pascual, Fernando, Redondo-Horcajo, Mariano, Magán-Marchal, Noemi, Lagares, David, Martínez-Ruiz, Antonio, Kleinert, Hartmut, Lamas, Santiago
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593384/
https://ncbi.nlm.nih.gov/pubmed/18809573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01145-08
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