Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome

Nucleophosmin (NPM) (B23) is an essential protein in mouse development and cell growth; however, it has been assigned numerous roles in very diverse cellular processes. Here, we present a unified mechanism for NPM's role in cell growth; NPM directs the nuclear export of both 40S and 60S ribosom...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maggi, Leonard B., Kuchenruether, Michael, Dadey, David Y. A., Schwope, Rachel M., Grisendi, Silvia, Townsend, R. Reid, Pandolfi, Pier Paolo, Weber, Jason D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593371/
https://ncbi.nlm.nih.gov/pubmed/18809582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01548-07
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg