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RAG2(−/−)γ(c)(−/−) Mice Transplanted with CD34(+) Cells from Human Cord Blood Show Low Levels of Intestinal Engraftment and Are Resistant to Rectal Transmission of Human Immunodeficiency Virus

Rectal transmission is one of the main routes of infection by human immunodeficiency virus type 1 (HIV-1). To efficiently study transmission mechanisms and prevention strategies, a small animal model permissive for rectal transmission of HIV is mandatory. We tested the susceptibility of RAG2(−/−)γ(c...

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Bibliografiske detaljer
Main Authors: Hofer, Ursula, Baenziger, Stefan, Heikenwalder, Mathias, Schlaepfer, Erika, Gehre, Nadine, Regenass, Stephan, Brunner, Thomas, Speck, Roberto F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593344/
https://ncbi.nlm.nih.gov/pubmed/18842716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01105-08
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