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RAG2(−/−)γ(c)(−/−) Mice Transplanted with CD34(+) Cells from Human Cord Blood Show Low Levels of Intestinal Engraftment and Are Resistant to Rectal Transmission of Human Immunodeficiency Virus
Rectal transmission is one of the main routes of infection by human immunodeficiency virus type 1 (HIV-1). To efficiently study transmission mechanisms and prevention strategies, a small animal model permissive for rectal transmission of HIV is mandatory. We tested the susceptibility of RAG2(−/−)γ(c...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Microbiology (ASM)
2008
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593344/ https://ncbi.nlm.nih.gov/pubmed/18842716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01105-08 |
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