Functional Pseudotyping of Human Immunodeficiency Virus Type 1 Vectors by Western Equine Encephalitis Virus Envelope Glycoprotein

We investigated the ability of western equine encephalitis virus envelope glycoproteins (WEEV GP) to pseudotype lentiviral vectors. The titers of WEEV GP-pseudotyped human immunodeficiency virus type 1 (HIV) ranged as high as 8.0 × 10(4) IU/ml on permissive cells. Sera from WEEV-infected mice specif...

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Detalhes bibliográficos
Main Authors: Poluri, Ananthalakshmi, Ainsworth, Rebecca, Weaver, Scott C., Sutton, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Gene Delivery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593314/
https://ncbi.nlm.nih.gov/pubmed/18842711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01503-08
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