Envelope Glycoprotein Mutations Mediate Equine Amplification and Virulence of Epizootic Venezuelan Equine Encephalitis Virus

Epidemics of Venezuelan equine encephalitis (VEE) result from high-titer equine viremia of IAB and IC subtype viruses that mediate increased mosquito transmission and spillover to humans. Previous genetic studies suggest that mutations in the E2 envelope glycoprotein allow relatively viremia-incompe...

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Autors principals: Greene, Ivorlyne P., Paessler, Slobodan, Austgen, Laura, Anishchenko, Michael, Brault, Aaron C., Bowen, Richard A., Weaver, Scott C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168750/
https://ncbi.nlm.nih.gov/pubmed/15994807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.9128-9133.2005
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