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Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro.

Clostridium difficile is recognized as the major cause of antibiotic-associated colitis. C. difficile produces two toxins, A (enterotoxin) and B (cytotoxin), that are implicated in the pathogenesis of the colitis. We examined the dose responses, time course, and synergism of these two toxins in liga...

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Detalhes bibliográficos
Main Authors: Lima, A A, Lyerly, D M, Wilkins, T D, Innes, D J, Guerrant, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC259330/
https://ncbi.nlm.nih.gov/pubmed/3343050
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