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In Vivo DNA Protection by Relaxed-Specificity SinI DNA Methyltransferase Variants

The SinI DNA methyltransferase, a component of the SinI restriction-modification system, recognizes the sequence GG(A/T)CC and methylates the inner cytosine to produce 5-methylcytosine. Previously isolated relaxed-specificity mutants of the enzyme also methylate, at a lower rate, GG(G/C)CC sites. In...

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Bibliografiske detaljer
Main Authors: Tímár, Edit, Venetianer, Pál, Kiss, Antal
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593204/
https://ncbi.nlm.nih.gov/pubmed/18849437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00754-08
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