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In Vivo DNA Protection by Relaxed-Specificity SinI DNA Methyltransferase Variants
The SinI DNA methyltransferase, a component of the SinI restriction-modification system, recognizes the sequence GG(A/T)CC and methylates the inner cytosine to produce 5-methylcytosine. Previously isolated relaxed-specificity mutants of the enzyme also methylate, at a lower rate, GG(G/C)CC sites. In...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593204/ https://ncbi.nlm.nih.gov/pubmed/18849437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00754-08 |
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