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Computational Structure-Activity Relationship Analysis of Non-peptide Inducers of Macrophage Tumor Necrosis Factor-α Production

Previously, we screened a series of arylcarboxylic acid hydrazide derivatives for their ability to induce macrophage tumor necrosis factor α (TNF-α) production and identified 16 such compounds. In the present study, we evaluated 23 additional arylcarboxylic acid hydrazides and found that seven of th...

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Détails bibliographiques
Auteurs principaux: Khlebnikov, Andrei I., Schepetkin, Igor A., Kirpotina, Liliya N., Quinn, Mark T.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593147/
https://ncbi.nlm.nih.gov/pubmed/18815052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.08.078
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