Minimal Pharmacokinetic Interaction between the Human Immunodeficiency Virus Nonnucleoside Reverse Transcriptase Inhibitor Etravirine and the Integrase Inhibitor Raltegravir in Healthy Subjects

Etravirine, a next-generation nonnucleoside reverse transcriptase inhibitor, and raltegravir, an integrase strand transfer inhibitor, have separately demonstrated potent activity in treatment-experienced, human immunodeficiency virus (HIV)-infected patients. An open-label, sequential, three-period s...

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Main Authors: Anderson, Matt S., Kakuda, Thomas N., Hanley, William, Miller, Jutta, Kost, James T., Stoltz, Randall, Wenning, Larissa A., Stone, Julie A., Hoetelmans, Richard M. W., Wagner, John A., Iwamoto, Marian
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592888/
https://ncbi.nlm.nih.gov/pubmed/18838586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00487-08
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