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Pharmacodynamics of Minocycline against Staphylococcus aureus in an In Vitro Pharmacokinetic Model

Free drug serum concentrations of minocycline associated with the doses given to humans (100 mg every 12 hours for 24 hours) were simulated in an in vitro hollow-fiber pharmacokinetic model. Four strains of methicillin (meticillin)-resistant Staphylococcus aureus (MRSA), United Kingdom EMRSA 15 and...

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Autors principals: Bowker, Karen E., Noel, Alan R., MacGowan, Alasdair P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592882/
https://ncbi.nlm.nih.gov/pubmed/18519719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00922-07
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