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FAM29A promotes microtubule amplification via recruitment of the NEDD1–γ-tubulin complex to the mitotic spindle

Microtubules (MTs) are nucleated from centrosomes and chromatin. In addition, MTs can be generated from preexiting MTs in a γ-tubulin–dependent manner in yeast, plant, and Drosophila cells, although the underlying mechanism remains unknown. Here we show the spindle-associated protein FAM29A promotes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Hui, Coppinger, Judith A., Jang, Chang-Young, Yates, John R., Fang, Guowei
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592839/
https://ncbi.nlm.nih.gov/pubmed/19029337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200807046
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