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Self-Interaction Is Critical for Atg9 Transport and Function at the Phagophore Assembly Site during Autophagy

Autophagy is the degradation of a cell's own components within lysosomes (or the analogous yeast vacuole), and its malfunction contributes to a variety of human diseases. Atg9 is the sole integral membrane protein required in formation of the initial sequestering compartment, the phagophore, an...

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Hlavní autoři: He, Congcong, Baba, Misuzu, Cao, Yang, Klionsky, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592676/
https://ncbi.nlm.nih.gov/pubmed/18829864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0544
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