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A GENOME-WIDE EXPLORATION SUGGESTS AN OLIGOGENIC MODEL OF INHERITANCE FOR THE TAFI ACTIVITY AND ITS ANTIGEN LEVELS

Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) is a protein that attenuates fibrinolysis potently. A considerable proportion of its variability levels is genetically determined. It has been associated with arterial and venous thrombosis. We conducted a genomewide linkage scan for genes affecting...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sabater-Lleal, Maria, Buil, Alfonso, Souto, Juan Carlos, Almasy, Laura, Borrell, Montserrat, Lathrop, Mark, Blangero, John, Fontcuberta, Jordi, Soria, José Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592198/
https://ncbi.nlm.nih.gov/pubmed/18563448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-008-0527-3
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