Sex-Specific Regulation of Mitochondrial DNA Levels: Genome-Wide Linkage Analysis to Identify Quantitative Trait Loci

Altered mitochondrial DNA (mtDNA) levels have been associated with common diseases in humans. We investigated the genetic mechanism that controls mtDNA levels using genome-wide linkage analyses in families from the Genetic Analysis of Idiopathic Thrombophilia Project (GAIT). We measure mtDNA levels...

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Main Authors: López, Sonia, Buil, Alfonso, Souto, Juan Carlos, Casademont, Jordi, Blangero, John, Martinez-Perez, Angel, Fontcuberta, Jordi, Lathrop, Mark, Almasy, Laura, Soria, Jose Manuel
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423410/
https://ncbi.nlm.nih.gov/pubmed/22916149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042711
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