Sex-Specific Regulation of Mitochondrial DNA Levels: Genome-Wide Linkage Analysis to Identify Quantitative Trait Loci

Altered mitochondrial DNA (mtDNA) levels have been associated with common diseases in humans. We investigated the genetic mechanism that controls mtDNA levels using genome-wide linkage analyses in families from the Genetic Analysis of Idiopathic Thrombophilia Project (GAIT). We measure mtDNA levels...

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Detalhes bibliográficos
Main Authors: López, Sonia, Buil, Alfonso, Souto, Juan Carlos, Casademont, Jordi, Blangero, John, Martinez-Perez, Angel, Fontcuberta, Jordi, Lathrop, Mark, Almasy, Laura, Soria, Jose Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423410/
https://ncbi.nlm.nih.gov/pubmed/22916149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042711
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