Cytokine regulation of murine leishmaniasis: interleukin 4 is not sufficient to mediate progressive disease in resistant C57BL/6 mice.

Neutralization of interleukin 4 (IL-4) at the time of infection with Leishmania major allowed susceptible BALB/c mice to heal. Recombinant IL-4, however, had little effect on the course of L. major infection in resistant C57BL/6 mice, nor did coinfection with Nippostrongylus brasiliensis, despite ma...

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Publicat a:Infect Immun
Autors principals: Sadick, M D, Street, N, Mosmann, T R, Locksley, R M
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1991
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259104/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1937832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.12.4710-4714.1991
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