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Crystal structure of an RNA aptamer bound to thrombin
Aptamers, an emerging class of therapeutics, are DNA or RNA molecules that are selected to bind molecular targets that range from small organic compounds to large proteins. All of the determined structures of aptamers in complex with small molecule targets show that aptamers cage such ligands. In st...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2590953/ https://ncbi.nlm.nih.gov/pubmed/18971322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1239308 |
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