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Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase

In recent years, dihydrodipicolinate synthase (DHDPS, E.C. 4.2.1.52) has received considerable attention from a mechanistic and structural viewpoint. DHDPS catalyzes the reaction of (S)-aspartate-β-semialdehyde with pyruvate, which is bound via a Schiff base to a conserved active-site lysine (Lys161...

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Hlavní autoři: Dobson, Renwick C.J., Griffin, Michael D.W., Devenish, Sean R.A., Pearce, F. Grant, Hutton, Craig A., Gerrard, Juliet A., Jameson, Geoffrey B., Perugini, Matthew A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590918/
https://ncbi.nlm.nih.gov/pubmed/18787203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.037440.108
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