Night Blindness and the Mechanism of Constitutive Signaling of Mutant G90D Rhodopsin

The G90D rhodopsin mutation is known to produce congenital night blindness in humans. This mutation produces a similar condition in mice, because rods of animals heterozygous (D+) or homozygous (D+/+) for this mutation have decreased dark current and sensitivity, reduced Ca(2+), and accelerated valu...

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Detalhes bibliográficos
Main Authors: Dizhoor, Alexander M., Woodruff, Michael L., Olshevskaya, Elena V., Cilluffo, Marianne C., Cornwall, M. Carter, Sieving, Paul A., Fain, Gordon L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590870/
https://ncbi.nlm.nih.gov/pubmed/18987202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4006-08.2008
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