Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke

Intracranial hemorrhage (ICH) is a particularly severe form of stroke whose etiology remains poorly understood, with a highly variable appearance and onset of the disease (Felbor et al., 2006; Frizzell, 2005; Lucas et al., 2003). In humans, mutations in any one of three CCM genes causes an autosomal...

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Bibliografiska uppgifter
Huvudupphovsmän: Gore, Aniket V., Lampugnani, Maria Grazia, Dye, Louis, Dejana, Elisabetta, Weinstein, Brant M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Limited 2008
Ämnen:
Research Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590810/
https://ncbi.nlm.nih.gov/pubmed/19093037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.000513
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