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Double-Mutant Cycle Scanning of the Interaction of a Peptide Ligand and its G Protein-Coupled Receptor
The interaction between the yeast G protein coupled receptor (GPCR), Ste2p, and its α-factor tridecapeptide ligand was subjected to double-mutant cycle scanning analysis by which the pairwise interaction energy of each ligand residue with two receptor residues, N205 and Y266, was determined. The mut...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2590777/ https://ncbi.nlm.nih.gov/pubmed/17298081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi602415u |
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