p66(Shc)-generated Oxidative Signal Promotes Fat Accumulation

Reactive oxygen species (ROS) and insulin signaling in the adipose tissue are critical determinants of aging and age-associated diseases. It is not clear, however, if they represent independent factors or they are mechanistically linked. We investigated the effects of ROS on insulin signaling using...

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Bibliographic Details
Main Authors: Berniakovich, Ina, Trinei, Mirella, Stendardo, Massimo, Migliaccio, Enrica, Minucci, Saverio, Bernardi, Paolo, Pelicci, Pier Giuseppe, Giorgio, Marco
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Metabolism and Bioenergetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590696/
https://ncbi.nlm.nih.gov/pubmed/18838380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804362200
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