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PRIMING DONOR LUNGS WITH THIOREDOXIN ATTENUATES ACUTE ALLOGRAFT INJURY IN A RAT MODEL OF LUNG TRANSPLANTATION

BACKGROUND: Lung graft dysfunction and rejection remain a significant cause of morbidity and mortality in transplant recipients. Thioredoxin-1 (Trx), a redox-regulatory protein, has been known to function as an antioxidant against oxidative injury in multiple organs including lungs. We examined whet...

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Detalhes bibliográficos
Main Authors: Hu, Hanbo, Lu, Li, Mu, Wei, Johnson, Richard J., Block, Edward R., Patel, Jawaharlal M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590662/
https://ncbi.nlm.nih.gov/pubmed/18926407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2008.07.006
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