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Genome wide microarray expression analysis of CD4+ T cells from NOD congenic mice identifies Cd55 (Daf1) and Acadl as candidate genes for type 1 diabetes

NOD.Idd3/5 congenic mice have insulin dependent diabetes (Idd) regions on chromosomes one (Idd5) and three (Idd3) respectively derived from the non-diabetic strains B10 and B6. NOD.Idd3/5 mice are almost completely protected from type 1 diabetes (T1D) but the genes within Idd3 and Idd5 responsible f...

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Autori principali: Irie, Junichiro, Reck, Brian, Wu, Yuehong, Wicker, Linda S., Howlett, Sarah, Rainbow, Daniel, Feingold, Eleanor, Ridgway, William M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590658/
https://ncbi.nlm.nih.gov/pubmed/18178847
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