Preparation, characterization, and immunogenicity of conjugates composed of the O-specific polysaccharide of Shigella dysenteriae type 1 (Shiga's bacillus) bound to tetanus toxoid.

The background for developing conjugate vaccines for shigellosis composed of the O-specific polysaccharide (O-SP) bound to a protein is described elsewhere (C. Y. Chu, R. Schneerson, and J. B. Robbins, submitted for publication). Briefly, there is direct evidence for type (lipopolysaccharide [LPS])-...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Chu, C Y, Liu, B K, Watson, D, Szu, S S, Bryla, D, Shiloach, J, Schneerson, R, Robbins, J B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1937803/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.12.4450-4458.1991
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