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Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes
BACKGROUND: In mammals the parental genomes are epigenetically reprogrammed after fertilization. This reprogramming includes a rapid demethylation of the paternal (sperm-derived) chromosomes prior to DNA replication in zygotes. Such active DNA demethylation in the zygote has been documented for seve...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2590599/ https://ncbi.nlm.nih.gov/pubmed/19014417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-1-8 |
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