Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

BACKGROUND: In mammals the parental genomes are epigenetically reprogrammed after fertilization. This reprogramming includes a rapid demethylation of the paternal (sperm-derived) chromosomes prior to DNA replication in zygotes. Such active DNA demethylation in the zygote has been documented for seve...

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Bibliographic Details
Main Authors: Lepikhov, Konstantin, Zakhartchenko, Valeri, Hao, Ru, Yang, Feikun, Wrenzycki, Christine, Niemann, Heiner, Wolf, Eckhard, Walter, Joern
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590599/
https://ncbi.nlm.nih.gov/pubmed/19014417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-1-8
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