CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction

CD4(+)CD25(+) T regulatory cells (T(regs)) play a central role in the suppression of immune responses thus serving to induce tolerance and to control persistent immune responses that can lead to autoimmunity. Here we explore if T(regs) also play a role in controlling the immediate hypersensitivity r...

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Main Authors: Gri, Giorgia, Piconese, Silvia, Frossi, Barbara, Manfroi, Vanessa, Merluzzi, Sonia, Tripodo, Claudio, Viola, Antonella, Odom, Sandra, Rivera, Juan, Colombo, Mario P., Pucillo, Carlo E.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590499/
https://ncbi.nlm.nih.gov/pubmed/18993084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.018
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