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Construction of minitransposons for constitutive and inducible expression of pertussis toxin in bvg-negative Bordetella bronchiseptica.

Appropriately detoxified pertussis toxin (PT) of Bordetella pertussis is considered to be an essential component of new-generation whooping cough vaccines, but the development of a procedure to obtain high levels of purified toxin has been and continues to be a major difficulty. To produce a system...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Walker, M J, Rohde, M, Wehland, J, Timmis, K N
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1682257/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.11.4238-4248.1991
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