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Single-dose tumor necrosis factor protection against endotoxin-induced shock and tissue injury in rats.

Tumor necrosis factor (TNF), a macrophage product released in response to endotoxin and other stimuli, has been shown to be a central mediator of endotoxin or septic shock. However, its highly conserved and wide-ranging physiological effects suggest that it may also be an essential cytokine in the h...

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Библиографические подробности
Опубликовано в::Infect Immun
Главные авторы: Alexander, H R, Doherty, G M, Block, M I, Kragel, P J, Jensen, J C, Langstein, H N, Walker, E, Norton, J A
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1937748/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.11.3889-3894.1991
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